• Charting a Course for Progress Institute of Medicine report calls for rigor and standardization (The Burrill Report)

    July 10, 2012 Some of the fastest evolving tools for evaluating the molecular and genetic underpinnings of disease are proving difficult to wield. Despite their great potential, it has been difficult to translate data generated through genomics, proteomics, and metabolomics into actual improvements in patient care.  In hopes of ... Read more
  • A Better Route for Diagnostics? (Drug Discovery & Development)

    June 12, 2012 From the moment of its inception, the Human Genome Project was expected to yield substantial benefits in diagnostics. But the genome is only part of the story. Equally important are the mRNA transcripts that carry out the genome’s orders, the proteins they encode, and ultimately, the ... Read more
  • Advances in Personalized Medicine for Lung Cancer (Science Daily)

    May 22, 2012 Several new studies that may help doctors tailor lung cancer treatment to the characteristics of individual patients and of their tumors are being presented at the 3rd European Lung Cancer Conference in Geneva. “A major goal of lung cancer treatment is to tailor the treatment to ... Read more
  • Protein Test Found to Boost NSCLC Survival, Costs (MedPage Today)

    January 16, 2012 This study found that choosing second-line therapy on the basis of a protein-expression test modestly improved survival in patients with advanced non-small cell lung cancer (NSCLC). The four- to six-week survival advantage held up in a sensitivity analysis involving 10,000 simulations. Choosing second-line therapy on the ... Read more
  • Trial Shows Biodesix Assay Predicts Breast Cancer Response to Femara (Genetic Engineering News)

    December 13, 2011 The use of Biodesix’ predictive cancer therapy assay VeriStrat has been validated in a Phase III trial originally carried out to evaluate GlaxoSmithKline’s Tykerb®/Tyverb® (lapatinib) as an addition to Novartis’ Femara® (letrozole) in breast cancer patients. Data from the trial demonstrated that VeriStrat could be used to identify a group of patients with worse progression-free survival (PFS) when treated with Femara ... Read more
  • Serum Profiling Making Mark on Predictive Medicine (Genetic Engineering News)

    April 4, 2011 Blood is a readily available and rich source of biomarkers that have the potential for use in diagnostics and companion diagnostics development, disease characterization and monitoring, and predictive drug response and toxicity analysis. Serum profiling using a variety of techniques to identify disease- or treatment-related proteins, antibodies, or oligonucleotides is leading ... Read more
  • Getting Personal (Clinical Lab Products)

    March 2, 2011 Personalized medicine, one goal of molecular diagnostics that is already being clinically realized, offers the opportunity to treat individuals on a case-by-case basis with greater efficacy and efficiency than ever before. Molecular diagnostics is heading the way of personalized medicine, aiming to help physicians devise particular treatment plans for individuals based on ... Read more
  • Biodesix Targeting Pharma for VeriStrat (GenomeWeb)

    January 24, 2011 As Biodesix continues clinical validation and commercialization of its test to predict patient response to therapies for non-small cell lung cancer, it is looking to forge pharmaceutical partnerships to increase adoption of the test. The company is in the midst of conducting a trial in Italy to determine whether the test ... Read more
  • Blood test helps target Roche/OSI lung cancer drug (Reuters)

    August 27, 2010 Blood analysis good at predicting how tumours will respond;  Proteomic test useful when doctors have no tumour tissue LONDON, April 30 (Reuters) – Testing for specific cancer protein markers in lung cancer patients’ blood helps find those more likely to respond to Tarceva, a drug sold by Roche (ROG.VX) and OSI Pharmaceuticals ... Read more
  • CBSA BioBreakfast Focuses on Two CO Success Stories of 2009 (Rocky Radar)

    May 21, 2010 CBSA’s May BioBreakfast allowed two of Colorado’s 2009 Bioscience success stories to share their stories.  First up was Paul Beresford of Biodesix, a company playing in the diagnostic space. Dr. Beresford spoke to the attendees about Biodesix’s successful introduction of VeriStrat, a ... Read more