<img src="https://ws.zoominfo.com/pixel/eCRg8hzy2qp0kNUl6E1g" width="1" height="1" style="display: none;">


MALDI-ToF Mass Spectrometry

Top-down proteomics approach for analyzing intact proteins in serum and plasma.

DeepMALDI® Overview

We have developed the DeepMALDI® system, a proprietary high-density matrix-assisted laser desorption/ionization time-of-flight (MALDI-ToF) mass spectrometry (MS) technology, to help overcome the limitations of conventional MALDI-ToF and other mass spectrometry methods by producing highly sensitive, stable, and reproducible data best suited for the discovery of diagnostic tests with clinical utility.

Key Benefits of DeepMALDI® Mass Spectrometry Analysis​

bdx-tube-icon Minimal Sample Input - as little as 20 μL of serum or plasma
bdx-check-icon High Likelihood of Proteomic Biomarker Discovery
bdx-multiplex-icon Highly Multiplexed & High Throughput
bdx-icon-differentiators-15 Differentiates Splice Variants & PTMs
bdx-target-icon Robust &
bdx-doctor-icon Established Clinical Diagnostic Test (VeriStrat® test)

VeriStrat®​ Test

  • Multivariate test that identifies the chronic elevation of acute phase reactants, which are known to be associated with aggressive cancer
  • Impacts treatment strategy and facilitates disease state monitoring

ImmunoStrat®​ Protein Signatures​

The ImmunoStrat® suite of protein signatures have been designed to interrogate a patient’s circulating proteome with the goal of predicting response to various immunotherapies across multiple tumor types.

Lung Cancer Risk of Recurrence Test

  • We have designed a pre-treatment blood-based protein signature that can identify stage I non-small cell lung cancer patients who have a high-risk of recurrence post-curative resection and may benefit from the addition of adjuvant therapy.
  • This test is currently in development.

Biological Pathway Protein Set Scoring

  • We have adapted the well-established methods of gene set enrichment analysis (GSEA) to understand protein pathways that are associated with different protein signature test results. ​
  • Pathways include: glycolytic processes, complement system, acute response, wound healing, interleukin-10 and immune response type II.

Custom Signature Discovery​

  • We design custom protein signatures with our proprietary AI platform to support our partners drug development programs.
  • These tests are designed to help answer specific clinical questions, including selecting patients for immunotherapies, novel therapy combinations, or alternative treatment pathways.

Get in touch

Contact Us

Data library

Discover More

* The images on our site are not representative of the Biodesix lab during COVID-19.